Details
Perioperative Inflammation as Triggering Origin of Metastasis Development
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CHF 177.00 |
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| Verlag: | Springer |
| Format: | |
| Veröffentl.: | 28.06.2017 |
| ISBN/EAN: | 9783319579436 |
| Sprache: | englisch |
Dieses eBook enthält ein Wasserzeichen.
Beschreibungen
<p>The book will explain previously unconnected clinical data such as why mammography works better for women age 50-59 than it does for women age 40-49, why adjuvant chemotherapy works best for premenopausal patients with positive lymph nodes, and it may also explain the racial disparity in outcome. In particular, it points to the perioperative period when systemic inflammation persists for a week or so. This can lead to a variety of mechanisms whereby single cancer cells (perhaps from the marrow) begin division and angiogenesis of dormant avascular micrometastases occurs leading to early relapses.</p><p>With chapters presented from distinguished scientists and physicians in a variety of specialties that relate to and border the effects we present, this volume can be used as a reference for practicing physicians and as a jumping-off point for researchers to explore new therapeutic opportunities.</p>
<div>Chapter 1. The Natural History of Breast Cancer</div><div>Chapter 2. Perioperative Inflammation as Triggering Origin of Metastasis Development </div><div>Chapter 3. Peri-operative Shift in Angiogenesis-Related Factors in Breast Cancer Patients</div><div>Chapter 4. Perioperative Biologic Perturbation and Cancer Surgery: Targeting the adrenergic-inflammatory response and microcirculatory dysregulation</div><div>Chapter 5. Circulating tumor cells as predictive marker in metastatic disease</div><div>Chapter 6. Randomized Clinical Trials on Breast Cancer in Nigeria and other Developing Countries- Challenges and Constraints<div>Chapter 7. Do Breast Cancer Patients Benefit from Surgery? Hypotheses, Mathematical Models and False Beliefs </div><div>Chapter 8. The impact of wound inflammation on cancer progression; Studies in fish and patients</div><div>Chapter 9. Long term consequences of acute inflammation in cancer surgery: New findings and perspectives</div><div>Chapter 10. Cancer: Nurture and Nature</div><div>Chapter 11. The systemic effects of local treatments (surgery and radiotherapy) of breast cancer</div></div>
<div><b>Michael Retsky, PhD,</b> is Research Associate, Harvard TH Chan School of Public Health and Honorary Faculty, University College London</div><div><br></div><div><b>Romano Demicheli, MD, PhD,</b> is Senior Researcher, Istituto Nazionale Tumori di Milano</div>
<p>The book will explain previously unconnected clinical data such as why mammography works better for women age 50-59 than it does for women age 40-49, why adjuvant chemotherapy works best for premenopausal patients with positive lymph nodes, and it may also explain the racial disparity in outcome. In particular, it points to the perioperative period when systemic inflammation persists for a week or so. This can lead to a variety of mechanisms whereby single cancer cells (perhaps from the marrow) begin division and angiogenesis of dormant avascular micrometastases occurs leading to early relapses.</p><p>With chapters presented from distinguished scientists and physicians in a variety of specialties that relate to and border the effects we present, this volume can be used as a reference for practicing physicians and as a jumping-off point for researchers to explore new therapeutic opportunities.</p>
<p>Will thoroughly explain previously unconnected clinical date such as why mammography works better for women age 50-59 than for women age 40-49;</p><p>Will explore why adjuvant chemotherapy works best for premenopausal patients with positive lymph nodes and may also explain the racial disparity in outcome;</p><p>Focuses on post-operative inflammation and its role in metastatic relapse.</p><p>Includes supplementary material: sn.pub/extras</p><p>Includes supplementary material: sn.pub/extras</p>
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