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Titration Calorimetry


Titration Calorimetry

From Concept to Application
SpringerBriefs in Molecular Science

von: Lee D. Hansen, Mark K. Transtrum, Colette F. Quinn

CHF 65.00

Verlag: Springer
Format: PDF
Veröffentl.: 06.04.2018
ISBN/EAN: 9783319782508
Sprache: englisch

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Beschreibungen

<p>This Brief describes&nbsp;the&nbsp;calibration of titration calorimeters (ITCs) and calculation of stoichiometry, equilibrium constants, enthalpy changes, and rate constants for reactions in solution.&nbsp; A framework/methodology for model development for analysis of ITC data is presented together with methods for assessing&nbsp;the uncertainties in determined parameters and test data sets. This book appeals&nbsp;to beginners, as well as&nbsp;to&nbsp;researchers and professionals in the field.</p><p></p>
<p>Chapter1: Introduction to Calorimetry.- Chapter2: Introduction to Titration Calorimetry.- Chapter3: Determination of Equilibrium Constants by Titration Calorimetry.- Chapter4: Determination of Reaction Kinetics by Calorimetry.- Chapter5: Statistics of Curve Fitting.- Chapter6: Related Topics in Calorimetry.- Chapter7: Self-test Questions.- Chapter8: Self-test Key.</p>
<p>Lee Hansen is Prof. Emeritus of Chemistry and Biochemistry at Brigham Young University in Provo, UT with more than 50 years experience developing instruments and methods for titration calorimetry.</p><p>Mark Transtrum is an Assistant Professor of Physics & Astronomy at Brigham Young University with interest in the theory of predictive modeling.&nbsp; Beyond modeling calorimetry data, he has developed theoretical and computational techniques to improve model analysis in the fields of physics, biology, power systems engineering, material science, and accelerator science.&nbsp;&nbsp;</p><p>Colette Quinn received her doctorate from Dartmouth College focusing on biophysical characterization. She spent many hours collecting ITC data in a glovebox and appreciates every time she can run an assay in an aerobic environment.</p>

<p></p>
<p>This Brief describes&nbsp;the&nbsp;calibration of titration calorimeters (ITCs) and calculation of stoichiometry, equilibrium constants, enthalpy changes, and rate constants for reactions in solution.&nbsp; A framework/methodology for model development for analysis of ITC data is presented together with methods for assessing&nbsp;the uncertainties in determined parameters and test data sets. This book appeals&nbsp;to beginners, as well as&nbsp;to&nbsp;researchers and professionals in the field.</p><p></p>

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