Details

Type IV Secretion in Gram-Negative and Gram-Positive Bacteria


Type IV Secretion in Gram-Negative and Gram-Positive Bacteria


Current Topics in Microbiology and Immunology, Band 413

von: Steffen Backert, Elisabeth Grohmann

CHF 165.50

Verlag: Springer
Format: PDF
Veröffentl.: 13.03.2018
ISBN/EAN: 9783319752419
Sprache: englisch

Dieses eBook enthält ein Wasserzeichen.

Beschreibungen

<div>Type IV secretion systems (T4SSs) are highly versatile membrane-associated transporter machines used by Gram-negative and Gram-positive bacteria to deliver substrate molecules to a large variety of target cells. This volume summarizes our current knowledge of the large variety and structural diversity of T4SSs in pathogenic Escherichia, Agrobacterium, Legionella, Coxiella, Bartonella, Helicobacter, Enterococcus and other species. Divided into 13 chapters contributed by leading experts, it presents findings that significantly enhance our understanding of how various pathogens manipulate host cell functions to trigger bacterial uptake, promote intracellular growth, suppress defense mechanisms and of how bacteria spread antibiotic resistances, thus facilitating bacterial colonization and disease development. The book is an invaluable source of information for researchers and clinicians.<br/></div>
<div>Biological diversity of prokaryotic type IV secretion systems.- Evolution of type IV secretion systems and their substrates.- Structural and molecular biology of type IV secretion systems.- Relaxosome formation and transfer of broad-host range plasmids Gram-negative bacteria.- Mechanisms of conjugative transfer by Gram-positive broad-host range plasmids.- Social behavior and decision making in bacterial conjugation.- Structure and chemical biology approaches to understand type IV secretion system function and inhibition.- Type IV secretion systems: A pivotal tool to establish intracellular lifestyle by pathogens.- Subversion of host target cells by the Legionella type IV secretion system.- Role of multiple type IV secretion systems in Bartonella infections.- Requirements for T4SS effector protein translocation and function by the Coxiella Dot/Icm system.- Composition and function of the Helicobacter pylori cag type IV secretion system.- Secretion of chromosomal DNA by the gonococcal type IV secretion system. </div><div><br/></div>
<p><b>Prof. Dr. rer. nat. Steffen Backert<br/> </b>Chair of Microbiology<br/> Friedrich Alexander University Erlangen/Nuremberg<br/> Department of Biology<br/>Division of Microbiology<br/>Staudtstr. 5<br/>D-91058 Erlangen<br/>Germany<br/>Tel.  ++49 9131 8528081<br/>Fax  ++49 9131 8528082 </p> <p><b>Prof. Dr. techn. Elisabeth Grohmann</b><b><br/></b>Professor of Microbiology<br/>Beuth University of Applied Sciences Berlin<br/>Department of Life Sciences and Technology<br/>Division of Microbiology<br/>Forum Seestraße<br/>Seestr. 64<br/>D-13347 Berlin<br/>Germany<br/>Tel. ++49 30 45043942<br/>Fax ++49 30 45043983</p>
Type IV secretion systems (T4SSs) are highly versatile membrane-associated transporter machines used by Gram-negative and Gram-positive bacteria to deliver substrate molecules to a large variety of target cells. This volume summarizes our current knowledge of the large variety and structural diversity of T4SSs in pathogenic Escherichia, Agrobacterium, Legionella, Coxiella, Bartonella, Helicobacter, Enterococcus and other species. Divided into 13 chapters contributed by leading experts, it presents findings that significantly enhance our understanding of how various pathogens manipulate host cell functions to trigger bacterial uptake, promote intracellular growth, suppress defense mechanisms and of how bacteria spread antibiotic resistances, thus facilitating bacterial colonization and disease development. The book is an invaluable source of information for researchers and clinicians.<p></p>
Offers new insights into the variety and structural diversity of type IV secretion systems Provides information on bacterial colonization and disease development Sheds new light on the manipulation of host cell functions by various pathogens

Diese Produkte könnten Sie auch interessieren:

The Biology of Echinostomes
The Biology of Echinostomes
von: Bernard Fried, Rafael Toledo
PDF ebook
CHF 177.00
Antibiotic Policies
Antibiotic Policies
von: Ian M. Gould, Jos W.M. van der Meer
PDF ebook
CHF 236.00
Tropical and Parasitic Infections in the Intensive Care Unit
Tropical and Parasitic Infections in the Intensive Care Unit
von: Charles Feldman, George A. Sarosi
PDF ebook
CHF 177.00