Details

<p>Preface xv</p> <p>Acknowledgments xvii</p> <p><b>1 EPIDERMIS 1</b></p> <p>Nevi 2</p> <p>Epidermal Nevus 2</p> <p>Variant: Inflammatory Linear Verrucous Epidermal Nevus (ILVEN) 3</p> <p>Keratoses 4</p> <p>Seborrheic Keratosis (SK) and Variants 4</p> <p>Variant: Acanthotic Seborrheic Keratosis 4</p> <p>Variant: Reticulated, Pigmented Seborrheic Keratosis 6</p> <p>Variant: Flat Seborrheic Keratosis 6</p> <p>Variant: Papillomatous Seborrheic Keratosis 7</p> <p>Variant: Activated (Irritated) Seborrheic Keratosis 7</p> <p>Variant: Dermatosis Papulosa Nigra 7</p> <p>Variant: Melanoacanthoma (Pigmented Seborrheic Keratosis) 8</p> <p>Variant: Clonal (Intraepidermal) Seborrheic Keratosis (Borst– Jadassohn) 9</p> <p>Variant: Seborrheic Keratosis with Monster Cells (Bowenoid) 10</p> <p>Variant: Hyperkeratotic Seborrheic Keratosis (Stucco Keratosis) 11</p> <p>Confluent and Reticulate Papillomatosis (Gougerot and Carteaud) 12</p> <p>Reticulate Pigmented Anomaly of the Flexures (Dowling–Degos Disease) 13</p> <p>Acanthosis Nigricans 14</p> <p>Solar (Actinic) Keratosis 15</p> <p>Variant: Acantholytic Solar Keratosis 16</p> <p>Variant: Atrophic Solar Keratosis 16</p> <p>Variant: Lichen Planus‐Like Solar Keratosis 17</p> <p>Variant: Hypertrophic (Bowenoid) Solar Keratosis 18</p> <p>Cornu Cutaneum 18</p> <p>Acanthomas, Non‐Viral 19</p> <p>Solar Lentigo 19</p> <p>Callus, Factitial Acanthoma 20</p> <p>Knuckle Pads (Chewing Pads) 21</p> <p>Pale (Clear) Cell Acanthoma 22</p> <p>Large Cell Acanthoma 23</p> <p>Differential Diagnosis: Epidermolytic Acanthoma 24</p> <p>Differential Diagnosis: Congenital Ichthyosiform Erythroderma 25</p> <p>Acantholytic Acanthoma 26</p> <p>Warty Dyskeratoma 27</p> <p>Porokeratoma (Porokeratosis Mibelli) 30</p> <p>Acanthomas, Viral 31</p> <p>Verruca Vulgaris 31</p> <p>Variant: Verruca Plana 33</p> <p>Variant: Condyloma Acuminatum 34</p> <p>Bowenoid Papulosis 35</p> <p>Acrokeratosis Verruciformis (Hopf) 37</p> <p>Molluscum Contagiosum 38</p> <p>“Pseudocarcinomas” and Neoplasms with Intermediate Malignant Potential 40</p> <p>Keratoacanthoma (KA) 40</p> <p>Epithelioma Cuniculatum (Verrucous Carcinoma) (EC/VC) 44</p> <p>Papillomatosis Cutis Carcinoides 45</p> <p>Florid Papillomatosis of the Oral Cavity (Oral Verrucous Carcinoma) 46</p> <p>Buschke–Löwenstein Tumor (Giant Condyloma) 47</p> <p>Malignant Epidermal Neoplasms 48</p> <p>Bowen’s Disease (Carcinoma in situ) 48</p> <p>Variant: Clear Cell Bowen’s Disease 50</p> <p>Variant: Cutaneous Horn (Cornu Cutaneum) on Bowen’s Disease 51</p> <p>Variant: Pigmented (Anogenital) and Clonal Bowen’s Disease 52</p> <p>Variant: Erythroplasia of Queyrat and Vulvar Intraepithelial Neoplasia 53</p> <p>Basal Cell Carcinoma (BCC) 54</p> <p>Variant: Nodular BCC 54</p> <p>Variant: Infundibulocystic BCC 56</p> <p>Variants of BCC With Ductal, Matrical or Sebaceous Differentiation 57</p> <p>Variant: Superficial BCC 60</p> <p>Variant: Pigmented BCC 61</p> <p>Variant: Adenoid‐Cystic BCC 62</p> <p>Variant: Sclerodermiform (Morpheaform) BCC 64</p> <p>Clinical Variants: Ulcerating BCCs 66</p> <p>Histological Variants: Metatypic BCC with Squamoid Differentiation 67</p> <p>Syndromatic BCC (Basal Cell Nevus Syndrome, Gorlin–Goltz) 69</p> <p>Fibroepithelioma of Pinkus 70</p> <p>Squamous Cell Carcinoma (SCC) 72</p> <p>Variant: Well‐Differentiated SCC 72</p> <p>Variant: Acantholytic SCC (Epithelioma Spinocellulare Segregans of Delacretaz) 74</p> <p>Variant: Myxoid SCC 76</p> <p>Variant: Follicular (Infundibular) SCC 77</p> <p>Variant: Spindle Cell (Fusicellular) SCC 78</p> <p>Squamous Cell Carcinomas in Special Sites 79</p> <p><b>2 ADNEXAL 85</b></p> <p>Sweat Gland Differentiation 86</p> <p>Nevi, Hyperplasias, and Benign Adnexal Neoplasms (BAN) 86</p> <p>Eccrine Differentiation 86</p> <p>Apocrine Differentiation 93</p> <p>Malignant Adnexal Neoplasms 105</p> <p>Eccrine Differentiation 105</p> <p>Apocrine Differentiation 109</p> <p>Sebaceous Differentiation 110</p> <p>Hyperplasias and Hamartomas 111</p> <p>Ectopic (Heterotopic) Sebaceous Glands (Fordyce Glands) 111</p> <p>(Senile) Sebaceous Gland Hyperplasia 112</p> <p>Nevus Sebaceous (Jadassohn) 113</p> <p>Variant: Pilo‐Sebaceous Hamartoma 114</p> <p>Benign Neoplasms 114</p> <p>Sebaceous Adenoma 114</p> <p>Muir–Torre Syndrome 115</p> <p>Sebaceous Epithelioma (Sebaceoma) 116</p> <p>Malignant Neoplasms 118</p> <p>Sebaceous Carcinoma 118</p> <p>Hair Follicle Differentiation 119</p> <p>Nevi, Hyperplasia, and Hamartomas 119</p> <p>Hair Follicle Nevus 119</p> <p>Conical Infundibular Acanthoma (Giant Dilated Pore of Winer) 120</p> <p>Benign Neoplasms 121</p> <p>Pilar Sheath Acanthoma 121</p> <p>Trichilemmoma (Tricholemmoma) 122</p> <p>Tumor of the Follicular Infundibulum (Infundibuloma) 124</p> <p>Trichoepithelioma (Superficial Trichoblastoma) 125</p> <p>Trichoblastoma (Trichoblastic Fibroma; Immature Trichoepithelioma) 127</p> <p>Trichoepithelioma (Sclerosing Epithelial Hamartoma) 131</p> <p>Trichofolliculoma (Folliculosebaceous Cystic Hamartoma) 133</p> <p>Trichoadenoma (Nikolowski) 136</p> <p>Pilomatricoma (Calcifying Epithelioma Malherbe) 137</p> <p>Proliferating Trichilemmal (Pilar) Tumor (PTT) (Proliferating Trichilemmal Cyst) 138</p> <p>Malignant Neoplasms 140</p> <p>Malignant Pilomatricoma (Pilomatrical Carcinoma) 140</p> <p>Trichilemmal Carcinoma 141</p> <p>Trichoblastic Carcinoma 142</p> <p>Pilosebaceous Mesenchyme 143</p> <p>Benign Neoplasm 143</p> <p>Trichodiscoma (Follicular Fibroma, Fibrofolliculoma, Perifollicular Fibroma) 143</p> <p><b>3 PAGET’S DISEASE 145</b></p> <p>Mammary Paget’s Disease 146</p> <p>Extramammary Paget’s Disease 146</p> <p><b>4 MELANOCYTES 149</b></p> <p>Non‐Neoplastic Hyperpigmentations 150</p> <p>Ephelides (Genuine Freckles) 150</p> <p>PUVA (Psoralen UVA) Lentigo 150</p> <p>“Nevus” Spilus (Speckled Lentiginous Nevus; Café‐Au‐Lait Spot) 151</p> <p>“Ink” Spot Lentigo (Reticulated Melanocytic Macule) 152</p> <p>Senile Freckles (Solar [Actinic] Lentigo) 153</p> <p>Mucosal Lentiginous Spots (Lip, Buccal, and Genital Mucosa) 154</p> <p>Nevi 155</p> <p>Common Acquired Melanocytic Nevi 155</p> <p>Melanosis Neviformis (Pigmented Hairy Epidermal Nevus; Becker Nevus) 155</p> <p>Junctional Nevus 156</p> <p>Compound Nevus 157</p> <p>Dermal Nevus 158</p> <p>Variant: Miescher’s Nevus (Dermal Nevus) 160</p> <p>Variant: Balloon Cell Nevus 161</p> <p>Variant: “Activated” Acral (Lentiginous) Melanocytic Nevus 161</p> <p>Variant: (Atypical) Genital Melanocytic Nevus 162</p> <p>Variant: Halo Nevus (Leukoderma Centrifugum Acquisitum; Sutton Nevus) 163</p> <p>Variant: Eczematoid Melanocytic (Meyerson’s) Nevus 165</p> <p>Variant: Osteo‐Nevus of Nanta 166</p> <p>Variant: Combined Epithelioid Spitzoid Nevus, “Wiesner Nevus” (BAP-1 Deficient Epithelioid Melanocytic Tumor) 167</p> <p>Variant: Recurrent (Persistent) Melanocytic Nevus (Pseudomelanoma) 167</p> <p>Variant: Nevus in Pregnancy 168</p> <p>Variant: Ancient Nevus 170</p> <p>Blue Nevi 171</p> <p>Common Blue Nevus 171</p> <p>Common Blue Nevus 172</p> <p>Dermal Melanocytosis 177</p> <p>Nevus Fuscoceruleus (Ota; Ito; Mongolian Spot) 177</p> <p>Spindle and/or Epithelioid Cell Nevus 178</p> <p>Common Nevus of Spitz 178</p> <p>Variants of Spindle and Epithelioid Cell Nevus 179</p> <p>Variant: Pigmented Spindle Cell Nevus (Reed) 182</p> <p>Benign Melanocytic Lesions with Peculiar Structural Features 183</p> <p>Melanocytic Nevus with Clonal Proliferation 183</p> <p>Atypical (Dysplastic) Melanocytic (Clark’s) Nevus (B‐K Mole Syndrome) 185</p> <p>Congenital Nevi, Small and Medium‐Sized (1.5–20 cm) 186</p> <p>Malignant Melanocytic Neoplasms 188</p> <p>Lentigo Maligna Dubreuilh (Hutchinson’s Freckle) 188</p> <p>Malignant Melanoma 189</p> <p>Variant: Superficial Spreading Melanoma (SSM) 190</p> <p>Variant: Lentigo Maligna Melanoma (LMM) 192</p> <p>Variant: Nodular Melanoma (NM) 193</p> <p>Variant: Acral Lentiginous Melanoma (ALM) 194</p> <p>Variant: Melanoma in Large Congenital Melanocytic Nevus (LCMN) 196</p> <p>Variant: Cutaneous Metastasis of Melanoma 197</p> <p>Special Localisations of Malignant Melanoma 204</p> <p>Tumor Thickness and Levels 205</p> <p>Common Clinical Differential Diagnoses of Malignant Melanoma 205</p> <p><b>5 CONNECTIVE TISSUE 207</b></p> <p>Nevi 208</p> <p>Connective Tissue Nevus (Shagreen Patch; Cobblestone Nevus; Nevus Collagenicus) 208</p> <p>Fibrous Neoplasms 209</p> <p>Soft Fibroma (Skin Tag; Acrochordon) 209</p> <p>Perifollicular Fibroma (Fibrofolliculoma; Trichodiscoma) 210</p> <p>Variant: Sclerotic Fibroma (Plywood Fibroma; Storiform Collagenoma) 211</p> <p>Variant: Fibrous Papule of the Nose 212</p> <p>Variant: Pleomorphic Sclerosing Fibroma with Multinucleated Cells 212</p> <p>Keloid 213</p> <p>Infantile Digital Fibromatosis (Inclusion Body Fibromatosis; Recurring Digital Fibrous Tumor of Children; Reye’s Tumor) 214</p> <p>Malformations with Supernumerary Tissue Elements 216</p> <p>Supernumerary Digit (Rudimentary Digit; Rudimentary Polydactyly) 216</p> <p>Differential Diagnosis: Acral Acquired Fibrokeratoma 216</p> <p>Accessory Tragus (Preauricular Tag) 217</p> <p>Accessory Nipple (Ectopic Breast; Polythelia) 218</p> <p>Fibrohistiocytic Neoplasms 218</p> <p>Dermatofibroma (Benign Fibrous Histiocytoma; Fibroma Durum; Sclerosing Hemangioma) 218</p> <p>Dermatofibrosarcoma Protuberans 227</p> <p>Variant: Pigmented Dermatofibrosarcoma Protuberans (Bednar’s Tumor) 230</p> <p>Variant: Giant Cell Fibroblastoma 231</p> <p>Pleomorphic Dermal Sarcoma (PDS) 231</p> <p>Miscellaneous Tumors 234</p> <p>Epithelioid Sarcoma 234</p> <p>Dermatomyofibroma 236</p> <p><b>6 VESSELS 239</b></p> <p>Hamartomas, Nevi, and Malformations 240</p> <p>Phacomatosis Pigmentovascularis 240</p> <p>Eccrine Angiomatous Hamartoma 241</p> <p>Nevus Anemicus 242</p> <p>Capillary Malformations 242</p> <p>Nevus Flammeus (Port-Wine Stain) 242</p> <p>Nevus Araneus (Spider Angioma) 244</p> <p>Cutis Marmorata Telangiectatica (van Lohuizen) (Nevus Vascularis Reticularis) 245</p> <p>Congenital Telangiectatic Erythema (Bloom’s Syndrome) 247</p> <p>Venous Malformations 248</p> <p>Blue Rubber Bleb Nevus Syndrome (Familial Venous Malformation) 248</p> <p>Hereditary Hemorrhagic Telangiectasia (Osler–Weber–Rendu) 249</p> <p>Angioma Serpiginosum 250</p> <p>Venular Aneurysm (Venous Lake) 251</p> <p>Cavernous Hemangioma (in Maffucci Syndrome) 252</p> <p>Sinusoidal Hemangioma 253</p> <p>Spindle Cell Hemangioma (Formerly Spindle Cell Hemangioendothelioma) 254</p> <p>Arteriovenous Malformations 256</p> <p>Acral Arteriovenous Hemangioma (Cirsoid Aneurysm) 256</p> <p>Glomuvenular Malformation (“Glomangioma”) 257</p> <p>Lymphatic Malformations 259</p> <p>Superficial Lymphatic Malformation (Superficial Lymphangioma) 259</p> <p>Cystic Lymphatic Malformation (Cystic Hygroma) 260</p> <p>Targetoid Hemosiderotic (Hobnail) Hemangioma 261</p> <p>Progressive Lymphangioma (Benign Lymphangioendothelioma) 262</p> <p>Lymphangiomatosis 263</p> <p>Angiokeratomas 264</p> <p>Verrucous Hemangioma (Venous Malformation) 265</p> <p>Variant: Solitary Angiokeratoma 268</p> <p>Variant: Angiokeratoma Circumscriptum Naeviformis 269</p> <p>Variant: Fordyce Angiokeratoma 269</p> <p>Variant: Angiokeratoma Acroasphycticum Digitorum (Mibelli) 269</p> <p>Variant: Multiple “Pinpoint” Angiokeratomas (Angiokeratoma Corporis Diffusum; Fabry’s Disease) 269</p> <p>Variant: Acral Pseudolymphomatous Angiokeratoma of Children (APACHE) 269</p> <p>Hyperplasias 270</p> <p>Granuloma Pyogenicum (Lobular Capillary Hemangioma; Botryomykoma) 270</p> <p>Differential Diagnosis: Pyogenic Granuloma‐Like Granulation Tissue 272</p> <p>Bacillary Angiomatosis 273</p> <p>Verruga Peruana 274</p> <p>Intravascular Papillary Endothelial Hyperplasia (Masson) 275</p> <p>Acroangiodermatitis Mali (Pseudo‑Kaposi’s Sarcoma) 276</p> <p>Benign Vascular Neoplasms 278</p> <p>Epithelioid Hemangioma (Angiolymphoid Hyperplasia with Eosinophilia, ALHE) 278</p> <p>Endothelial Differentiation 280</p> <p>Infantile Capillary and Congenital Hemangioma 280</p> <p>Cherry Angioma (Senile Hemangioma) 281</p> <p>Microvenular (Microcapillary) Hemangioma 282</p> <p>Tufted Angioma 283</p> <p>Kaposiform Hemangioendothelioma 285</p> <p>Glomeruloid Hemangioma in POEMS Syndrome 287</p> <p>Pericytic Differentiation 288 Imitator: Solitary Fibrous Tumor of the Skin (SFT) 289</p> <p>Myopericytoma (Infantile Myofibromatosis; Perivascular Myoma (incl. Myofibroma)) 290</p> <p>Glomoid and Myoid Differentiation 292</p> <p>Glomus Tumor 292</p> <p>Angioleiomyoma (Angiomyoma; Vascular Leiomyoma) 294</p> <p>Recently Described Benign Vascular Tumors 296</p> <p>Symplastic Hemangioma 296</p> <p>Papillary Hemangioma 297</p> <p>Vascular Neoplasms of Intermediate Malignant Potential 298</p> <p>Kaposi’s Sarcoma (KS) 298</p> <p>Retiform Hemangioendothelioma 305</p> <p>Composite Hemangioendothelioma 306</p> <p>Papillary Intralymphatic Angioendothelioma (PILA) (Malignant Endovascular Papillary Angioendothelioma (Dabska Tumor); Endovascular Papillary Hemangioendothelioma) 306</p> <p>Radiation‐Induced Atypical Vascular Lesion (AVL) (Benign Lymphangiomatous Papule (BLAP)) 308</p> <p>Vascular Neoplasms with High Malignant Potential 309</p> <p>Cutaneous Angiosarcoma 309</p> <p>Radiation‐Induced (Postradiation) Angiosarcoma 312</p> <p>Epithelioid Hemangioendothelioma 312</p> <p>Epithelioid Angiosarcoma 315</p> <p>Differential Diagnosis: Acantholytic (Angiosarcoma‐Like) Squamous Cell Carcinoma 316</p> <p>Glomangiosarcoma (Malignant Glomus Tumor) 317</p> <p>Other Neoplasms with Significant Vascular Component 318</p> <p>Multinucleate Angiohistiocytoma 318</p> <p>Angiofibroma (Adenoma Sebaceum Associated with Pringle–Bourneville Disease) 319</p> <p>Angiolipoma 321</p> <p>Angiolipoleiomyoma (Angiomyolipoma) 322</p> <p>Angiomyxoma 322</p> <p>Intralymphatic Histiocytosis 324</p> <p>Kimura’s Disease 325</p> <p><b>7 FAT 327</b></p> <p>Nevus (Hamartoma) 328</p> <p>Nevus Lipomatosus Superficialis Hoffmann Zurhelle 328</p> <p>Neoplasms of Fat Tissue 329</p> <p>Benign Neoplasms 329</p> <p>Common Lipoma and Lipomatosis 329</p> <p>Angiolipoma (see Vessels, Chapter 6) 330</p> <p>Angiomyolipoma (see Vessels, Chapter 6) 330</p> <p>Spindle Cell Lipoma 330</p> <p>Pleomorphic Lipoma (see Pleomorphic Liposarcoma) 332</p> <p>Hibernoma 332</p> <p>Malignant Neoplasms 333</p> <p>Cutaneous Liposarcoma 333</p> <p><b>8 MUSCLE 337</b></p> <p>Benign Neoplasms 338</p> <p>Piloleiomyoma (Pilar Leiomyoma) 338</p> <p>Angioleiomyoma (see Vessels, Chapter 6) 340</p> <p>Rhabdomyoma, Adult Type 340</p> <p>Malignant Neoplasms 341</p> <p>Rhabdomyosarcoma 341</p> <p>Superficial Leiomyosarcoma 342</p> <p><b>9 NERVES 345</b></p> <p>Benign Neoplasms 346</p> <p>Schwannoma (Neurilemmoma) 349</p> <p>Solitary Neuroma (“Palisaded Encapsulated Neuroma”) 352</p> <p>Variant: Traumatic Neuroma 353</p> <p>Granular Cell Tumor (Abrikossoff) 354</p> <p>Dermal Nerve Sheath Myxoma (Myxoid Neurothekeoma) 356</p> <p>Variant: Cellular Neurothekeoma 357</p> <p>Pacinian Neurofibroma (Pacinoma) 358</p> <p>Malignant Neoplasms 358</p> <p>Malignant Peripheral Nerve Sheath Tumor (Malignant Schwannoma) 358</p> <p>Malignant Granular Cell Tumor 360</p> <p>Neuroendocrine Neoplasm 360</p> <p>Primary Neuroendocrine (Merkel Cell, Trabecular) Carcinoma of the Skin 360</p> <p><b>10 MAST CELLS 363</b></p> <p>Solitary Cutaneous Mast Cell Proliferation 364</p> <p>Cutaneous Mastocytoma 364</p> <p>Diffuse Cutaneous Mast Cell Proliferations 365</p> <p>Urticaria Pigmentosa (Juvenile Maculopapular Mastocytosis) 365</p> <p>Telangiectasia Macularis Eruptiva Perstans (Adults) 365</p> <p>Systemic Mast Cell Proliferation 367</p> <p>Involvement of Skin and Bone Marrow 367</p> <p><b>11 HISTIOCYTES 369</b></p> <p>Langerhans Cell Histiocytoses (LCH) 370</p> <p>Precursors of Langerhans Cell Histiocytoses 370</p> <p>Congenital Self‐healing Reticulohistiocytosis (Hashimoto–Pritzker) 370</p> <p>Indeterminate Cell Histiocytosis 371</p> <p>Langerhans Cell Histiocytoses (Histiocytosis X) 371</p> <p>Congenital Langerhans Cell Histiocytosis (Letterer–Siwe Disease) 372</p> <p>Hand–Schüller–Christian Adult LHC Histiocytosis 374</p> <p>Solitary Langerhans Cell Tumor (Eosinophilic Granuloma) 375</p> <p>Non‐Langerhans Cell Histiocytoses 376</p> <p>Proliferative 376</p> <p>Proliferative Histiocytoma (Progressive Nodular Histiocytosis, PNH) 376</p> <p>Benign Cephalic Histiocytosis 377</p> <p>Multicentric Reticulohistiocytosis (Lipoid Dermatoarthritis) (Solitary Reticulohistiocytoma) 378</p> <p>Sinus Histiocytosis With Massive Lymphadenopathy 379</p> <p>Granulomatous Storing 380</p> <p>Juvenile Xanthogranuloma (Nevoxanthoendothelioma; Xanthoma Multiplex; Juvenile Giant Cell Granuloma) 380</p> <p>Xanthelasma Palpebrarum 383</p> <p>Verruciform Xanthoma 384</p> <p>Necrobiotic Xanthogranuloma (with Paraproteinemia) 385</p> <p>Hereditary Progressive Mucinous Histiocytosis 386</p> <p>Hemophagocytic 387</p> <p>Familial Hemophagocytic Lymphohistiocytosis 387</p> <p>Histiocytic Cytophagic Panniculitis 388</p> <p><b>12 HEMATOPOIETIC DISORDERS 389</b></p> <p>Lymphoid Skin Infiltrates 389</p> <p>Cytomorphology, Major Cell Types 390</p> <p>T‐Cells 390</p> <p>B‐Cells 391</p> <p>Pattern of Small Cell Lymphocytic Infiltrates 392</p> <p>T‐Cell Pattern 392</p> <p>B‐Cell Pattern 392</p> <p>Pseudolymphoma (PL) 393</p> <p>Nodular B‐Cell PL 393</p> <p>Lymphadenosis Cutis Benigna (Lymphocytoma Cutis) 393</p> <p>Differentiation between B‑Pseudolymphoma (PL) and Cutaneous B‐Cell Lymphoma (CBCL) 395</p> <p>Nodular T‐Cell PL 396</p> <p>CD30+ Pseudolymphoma in Scabies 396</p> <p>Papular (Secondary) Syphilis 398</p> <p>Pseudo‐Mycosis Fungoides (Mycosis Fungoides Simulators) 399</p> <p>Lymphomatoid Contact Dermatitis 399</p> <p>Lichen Planus 399</p> <p>Drug Reactions 400</p> <p>Early Vitiligo 400</p> <p>Lichen Sclerosus et Atrophicus 400</p> <p>Pityriasis Lichenoides Chronica 401</p> <p>Graft Versus Host Reaction (Acute) 401</p> <p>Pityriasis Lichenoides et Varioliformis Acuta (PLEVA) 402</p> <p>Pigmented Purpuric Dermatitis (Lichen Aureus) 403</p> <p>Lymphocytic Infiltration Jessner–Kanof 404</p> <p>Cutaneous Mature T‐Cell Lymphoid Neoplasms (CTCL) 405</p> <p>Mycosis Fungoides, Classic Alibert–Bazin Type 405</p> <p>Mycosis Fungoides Patch Stage I 405</p> <p>Mycosis Fungoides Plaque Stage II (CD4+; CD8−) 407</p> <p>Variant: CD8+ Mycosis Fungoides 409</p> <p>Mycosis Fungoides Tumor Stage III 409</p> <p>Large Cell Transformation 410</p> <p>Simulators and Variants of Mycosis Fungoides: “Parapsoriasis” 411</p> <p>Simulator: Small Plaque Parapsoriasis (SPP) (Brocq’s Disease, Digitate Dermatosis) 411</p> <p>Large Plaque Parapsoriasis (LPP) 412</p> <p>Pigmented Purpuric Mycosis Fungoides 412</p> <p>Erythrodermic Mycosis Fungoides 412</p> <p>Folliculotropic (Pilotropic) Mycosis Fungoides 413</p> <p>Syringotropic Mycosis Fungoides (Syringolymphoid Hyperplasia with Alopecia) 414</p> <p>Granulomatous Mycosis Fungoides 415</p> <p>Granulomatous Slack Skin 415</p> <p>Pagetoid Reticulosis (PR), Unilesional (Woringer–Kolopp) 417</p> <p>Sézary Syndrome (SS) 418</p> <p>Variant: Sézary Syndrome, Large Cell Transformation 420</p> <p>CD30‐Positive Lymphoproliferative Disorders (LPD) of the Skin 423</p> <p>Anaplastic Large Cell Lymphoma (ALCL) 424</p> <p>Neutrophil‐Rich (Pyogenic) Anaplastic Large Cell Lymphoma 426</p> <p>Lymphomatoid Papulosis 427</p> <p>Differential Diagnosis: Hodgkin’s Lymphoma, Lymphocyte Predominance 429</p> <p>Subcutaneous Panniculitis‐Like Lymphoma 431</p> <p>Subcutaneous (Panniculitis-Like; Alpha/Beta) T‐Cell Lymphoma 431</p> <p>Differential Diagnosis: Subcutaneous (Panniculitis‐Like) Gamma/Delta lymphoma 432</p> <p>Differential Diagnosis: Lupus Panniculitis (Lupus Profundus) 433</p> <p>Primary Cutaneous Peripheral Lymphoma (PTL), Unspecified (NOS) 434</p> <p>Primary Cutaneous CD4‐positive (Acral) Small/Medium‐Sized T‐Cell Lymphoproliferative Disorder 435</p> <p>Cutaneous Aggressive Epidermotropic CD8‐positive T‐Cell Lymphoma (Berti) 436</p> <p>Differential Diagnosis: Febrile Ulceronecrotic PLEVA (Mucha–Habermann Disease) 437</p> <p>Extranodal NK/T‐Cell Lymphoma, Nasal Type (Subcutaneous) 439</p> <p>Hydroa Vacciniforme‐Like Lymphoma 440</p> <p>Angioimmunoblastic T‐Cell Lymphoma 441</p> <p>Cutaneous Mature B‐Cell Lymphoid Neoplasms (CBCL) 443</p> <p>Cutaneous Marginal Zone B‐Cell Lymphoma (MZL; MALT Type) 444</p> <p>Variant: Immunocytoma 447</p> <p>Differential Diagnoses: Multiple Myeloma/Plasmacytoma 448</p> <p>Primary Cutaneous Follicle Center Lymphoma (FCL) 449</p> <p>Diffuse Large B‐Cell Lymphoma (DLBCL) 451</p> <p>Variant: Cutaneous Diffuse Large B‐Cell Lymphoma (Leg Type) 451</p> <p>Variant: T‐Cell‐Rich B‐Cell Lymphoma (DLBCL) 454</p> <p>Cutaneous Spindle B‐Cell Lymphoma 455</p> <p>Extracutaneous B‐Cell Lymphoma (BCL) with Frequent Skin Involvement 457</p> <p>Mantle Cell Lymphoma 457</p> <p>Burkitt’s Lymphoma (BL) 458</p> <p>Lymphomatoid Granulomatosis (Liebow) (LYG) 460</p> <p>Intravascular Lymphomas 461</p> <p>Intravascular Large B‐Cell Lymphoma (IV‐LBCL) (Systemic Angioendotheliomatosis) 461</p> <p>Intravascular T Cell Lymphoma 462</p> <p>Secondary Skin Involvement in Leukemias/Lymphomas 463</p> <p>Chronic Lymphocytic Leukemia (CLL) 463</p> <p>Myeloid and Monocytic Leukemias 464</p> <p>T‐Zone Lymphoma 466</p> <p>Adult T‐Cell Leukemia/ Lymphoma (ATLL) 467</p> <p>Immature Hematopoietic Malignancies 468</p> <p>Blastic Plasmacytoid Dendritic Cell Neoplasm 468</p> <p>Precursor Lymphoblastic Leukemia/Lymphoma 470</p> <p><b>13 CUTANEOUS CYSTS 471</b></p> <p>Cysts with Epithelial Lining 472</p> <p>Stratified Squamous Epithelium 472</p> <p>Epidermal (Infundibular) Cysts 472</p> <p>Variant: Epidermal Proliferating Cyst 473</p> <p>Variant: Epidermal Cyst with Pigment and Vellus Hairs 473</p> <p>Vellus Hair Cyst 474</p> <p>Trichilemmal (Isthmus‐Catagen) Cyst 475</p> <p>Milia 476</p> <p>Follicular Hybrid Cyst 477</p> <p>Hidrocystoma (Cystadenoma) 478</p> <p>Steatocystoma, Multiplex and Simplex 481</p> <p>Dermoid Cyst 482</p> <p>Pilonidal Sinus (Pilonidal Cyst) 484</p> <p>Non‐Stratified Squamous Epithelium 485</p> <p>Cutaneous Ciliated Cyst of the Lower Limb 485</p> <p>Median Raphe Cyst 486</p> <p>Cysts without Epithelial Lining (Pseudocysts) 487</p> <p>Oral Mucous Cyst and Superficial Mucocele of the Lip 487</p> <p>Digital Myxoid Cyst 488</p> <p>Synovial Cyst (Ganglion) 490</p> <p>Index 491</p>

<p><b>Günter Burg,</b> <b>MD</b> is Professor of Dermatology and Chairman Emeritus, University of Zurich, Switzerland.</p> <p><b>Heinz Kutzner, </b><b>MD</b> is Professor of Dermatology, Institute of Dermatopathology, Friedrichshafen, Germany,</p> <p><b>Werner Kempf, </b><b>MD</b> is Professor of Dermatology, Department of Dermatopathology, University of Zurich, Switzerland.</p> <p><b>Josef Feit, MD</b> is Associate Professor of Pathology, University of Ostrava, Czech Republic.</p> <p><b>Bruce R. Smoller, MD</b> is Professor and Chairman of the Department of Pathology and Laboratory Medicine, University of Rochester, NY, School of Medicine and Dentistry.</p>

<p><b>A fully illustrated diagnostic aid for dermatologists and pathologists at all levels</b></p> <p>Differential diagnosis is at its most accurate and efficient when clinical presentation and histopathological features are considered in correlation with one another. With this being so, the expert team behind this atlas has integrated both perspectives to create an innovative and essential resource for all those involved with the diagnosis of tumors, cysts, and nevi. Almost 1,400 full-color images clearly illustrate common patterns and variants of tumorous lesions of the skin and are helpfully contextualized by concise, straightforward descriptions of key features and diagnostic clues.</p> <p>Whether they are aspiring or experienced practitioners, dermatologists and pathologists of all levels will find this an insightful and practically applicable addition to their bookshelf. Its far-reaching and easy-to-navigate coverage of relevant diseases of the skin provides trainees with an excellent grounding in the area, while practicing specialists may benefit from its use as a tool for the differential diagnoses of borderline cases. As with the authors’ previous work on inflammatory dermatoses, <i>Atlas of Dermatopathology: Practical Differential Diagnosis by Clinicopathologic Pattern</i>, this important text:</p> <ul> <li>Takes an effective, pattern-based approach to dermatologic diagnosis</li> <li>Matches clinical and histopathologic perspectives to give a fuller diagnostic picture</li> <li>Aids accurate diagnosis with almost 1,400 illustrative images</li> <li>Is written and designed to be easily consulted in everyday practice</li> <li>Presents contributions from internationally renowned dermatopathologists</li> </ul> <p><i>Atlas of Dermatopathology: Tumors, Nevi, and Cysts </i>offers a uniquely balanced, clear, and comprehensive guide to what can be a difficult process, and will be of tremendous assistance tostudents, dermatologists, dermatopathologists, and pathologists everywhere.</p>

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