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Clinical Use of Anti-infective Agents


Clinical Use of Anti-infective Agents

A Guide on How to Prescribe Drugs Used to Treat Infections
2nd ed. 2021

von: Robert W. Finberg, Roy Guharoy

CHF 130.00

Verlag: Springer
Format: PDF
Veröffentl.: 23.07.2021
ISBN/EAN: 9783030674595
Sprache: englisch

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Beschreibungen

<p>This second edition of Clinical Use of Anti-Infective Agents provides a comprehensive overview of current approaches to using drugs to treat infections, including historical perspectives, definitions, and discussion of pharmacokinetics and pharmacodynamics and their uses. It includes a detailed explanation of different classes of drugs, outlining their spectrum, pharmacokinetics, side effects, and dosing in clinical settings. This book has been designed as a reference tool for pharmacists, clinicians, nurse practitioners, and clinical microbiologists, as well as a teaching vehicle for students studying infection and patient treatment.<br></p><p>Each section includes references allowing for in-depth study of specific agents, Q&As, and illustrative case studies accompanied by commentary on how to approach patients and organisms, optimal methods of making a diagnosis, and prescribing treatment.</p>
1. Introduction and history.- 2. Basic principles of drug delivery and dosing.- 3. Sulfonamides.- 4. Penicillins.- 5. Cephalosporins.- 6. Monobactams: Aztreonam.- 7. Carbapenems.- 8. Glycopeptides and other agents used to treat gram-positive cocci.- 9. Vancomycin: New Area-under-the-curve-based therapeutic monitoring.- 10. Aminoglycosides.- 11. Macrolides.- 12. Metronidazole and clindamycin.- 13. Quinolones.- 14. Tetracyclines.- 15. Pleuromutilin.- 16. Antimicrobial stewardship: evolution into the 21st century.- 17. Clinical approach to the treatment of infectious diseases.- 18. Understanding drug allergies and drug toxicities.- 19. Antibiotic-associated diarrhea.- 20. Principles of antibiotic resistance.- 21. Clinical approach to treatment of bacterial infections.- 22. Clinical approach to treatment of mycobacterial infections.- 23. Clinical approach to treatment of fungal infections.- 24. Clinical approach to treatment of viral infections.- 25. Sample cases and analyses of the use ofanti-infective agents: Cases 1-15.- Appx A. Common infectious diseases and empiric antibiotic recommendations for adult ed and inpatients at UMass Memorial Medical Center.- Appx B. Bioavailability of anti-infective agents.- Appx C. Dosage and intervals for administration of IV antimicrobials.- Appx D. Dosage and intervals for administration of oral antimicrobials.- Appx E. Important interactions with commonly-used anti-infectives.- Appx F. Oral agents that may have interactions with food.- Appx G. Drug interactions with anti-retroviral agents.- Appx H. Dosage in obesity.- Appx I. Recommendations for management of Asymptomatic Bacteriuria (ASB): 2019 update.- Appx J. Guidelines for treatment of C. difficile.- Appx K. Antimicrobial prophylaxis for adult patients with cancer-related immunosuppression.- Appx L. Guidelines for treatment of adults with community-acquired pneumonia.- Appx M. Guidelines for management of adults with hospital-acquired and ventilator-associated pneumonia.- AppxN. Guidelines for antimicrobial prophylaxis for surgery.- Appx O. Guidelines for treatment and chemoprophylaxis of influenza.- Appx P. Antimicrobial dosing in adult patients on extracorporeal membrane oxygenation (EXMO).- Appx Q. Antimicrobial dosing in neonates.
Robert W. Finberg<div>Richard Haidack Professor and Chair</div><div>Department of Medicine</div><div>University of Massachusetts</div><div>Medical School</div><div>Worcester, MA, USA<br> Robert.Finberg@umassmed.edu</div><div><div><br></div><div>Roy Guharoy</div><div>System Vice President</div><div>Baptist Health System, Montgomery, AL</div><div>UMass Memorial Health Care Clinical Professor of Medicine&nbsp;</div><div>University of Massachusetts&nbsp;</div><div>Medical School&nbsp;</div><div>Worcester, MA, USA&nbsp;</div><div>Roy.Guharoy@umassmemorial.org</div></div>
<p>This second edition of Clinical Use of Anti-Infective Agents provides a comprehensive overview of current approaches to using drugs to treat infections, including historical perspectives, definitions, and discussion of pharmacokinetics and pharmacodynamics and their uses. It includes a detailed explanation of different classes of drugs, outlining their spectrum, pharmacokinetics, side effects, and dosing in clinical settings. This book has been designed as a reference tool for pharmacists, clinicians, nurse practitioners, and clinical microbiologists, as well as a teaching vehicle for students studying infection and patient treatment.</p><p>Each section includes references allowing for in-depth study of specific agents, Q&As, and illustrative case studies accompanied by commentary on how to approach patients and organisms, optimal methods of making a diagnosis, and prescribing treatment.</p>
Designed as a teaching vehicle for pharmacy, nursing, physician assistant, medical students and clinical practitioners Provides a quick-reference guide for pharmacists, nurse practitioners, and clinical microbiologists Features illustrative case studies, commentary, and study questions

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