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Organic Synthesis


Organic Synthesis

State of the Art 2005-2007
Organic Synthesis: State of the Art, Band 2 1. Aufl.

von: Douglass F. Taber

CHF 132.00

Verlag: Wiley
Format: PDF
Veröffentl.: 20.08.2008
ISBN/EAN: 9780470385968
Sprache: englisch
Anzahl Seiten: 240

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Beschreibungen

The second volume in a series, <i>Organic Synthesis: State of the Art 2005-2007</i> will provide you with a convenient, compact summary of the state of the art of organic synthesis. This reference guide will quickly lead you to the most important recent developments like how scientists can now prepare ketones by directly combining aldehydes with terminal alkenes. Inside, you will find detailed analysis of more than twenty total syntheses, including the Davies Synthesis of (-)-Colombiasin A and (-)-Elisapterosin B, the Overman Synthesis of (-)-Sarain A, and the Sorensen Synthesis of (-)-Guanacastepene E.
Preface. <p>1. Synthesis of (-)- Littoralisone.</p> <p>2. Enantiocontrolled Construction of Oxygenated and Animated Stereogenic Centers.</p> <p>3. Catalytic Enantioselective Construction of Alkylated Stereogenic Centers.</p> <p>4. Catalytic Enantioselective Aldol/Mannich Reactions Leading to Extended Arrays of Stereogenic Centers.</p> <p>5. Alternative Strategies for the Construction of Extended Arrays of Stereogenic Centers.</p> <p>6. Synthesis of(-)- Avrainvillamide and (+)- Stephacidin B.</p> <p>7. Best Synthetic Methods: Oxidation.</p> <p>8. Best Synthetic Methods: Reduction.</p> <p>9. Selective Reactions of Alkenes.</p> <p>10. Synthesis of the Potent FBBP12 Ligand Antascomicin B.</p> <p>11. Best Synthetic Methods: Carbon-Carbon Bond Formation.</p> <p>12. Enantioselective Construction of Quaternary Centers.</p> <p>13. Pd-Mediated Arylation of Aromatic and Hetero Aromatic Rings.</p> <p>14. The Overman Route to Gelsemine.</p> <p>15. Stereoselective Construction of Oxygen Heterocycles.</p> <p>16. Enantioselective Construction of Naturally-Occurring Cyclic Ethers.</p> <p>17. Stereoselective Construction of Nitrogen Heterocycles.</p> <p>19. The Stork Synthesis of (-)- Reserpine.</p> <p>19. Stereocontrolled Construction of Azacyclic Natural Products.</p> <p>20. Preparation of Benzene Derivatives.</p> <p>21. Preparation of Heteroaromatics.</p> <p>22. Preparation and Reactions of Carboxylic Acids, Esters and Amides.</p> <p>23. The Boger Route to (-)- Vindoline.</p> <p>24. Protection of C-O and C-N.</p> <p>25. New Catalysts and Strategies for Alkene Metathesis.</p> <p>26. Creative Applications of Alkene and Alkyne Metathesis in Total Synthesis: (+)-8<i>epi</i>-Xanthatin, (+)-Longicin, Latrunculin A, and Garsubellin A.</p> <p>27. Synthesis of Erythronolide A.</p> <p>28. Best Synthetic Methods: C-C Bond Formation.</p> <p>29. Catalytic Enantioselective Homologation of Aldehydes to Alcohols and Amines.</p> <p>30. Catalytic Enantioselective Construction of Alkylated Stereogenic Centers.</p> <p>31. Enantioselective Construction of Arrays of Stereogenic Centers.</p> <p>32. Adventures in Complex Indole Synthesis: (-)-Fixherindole I, (+)-Fischerindole G and (+)-Weltwitindolinone A.</p> <p>33. New Dienes and Dienophiles for Intermolecular and Intramolecular Diels-Alder Cycloaddtions.</p> <p>34. Organocatalytic Preparation of Enantiomerically-Pure Carbocycles.</p> <p>35. Carbocycle Construction by the Opening of Strained Rings: Synthesis of Tremulenolide A.</p> <p>36. The Corey Route to the Dolabellanes: Isoedunol and P-Araneosene.</p> <p>37. Transition-Metal Catalyzed Enantioselective Ring Construction.</p> <p>38. Best Synthetic Methods: Functional Group Transformation.</p> <p>39. Selective Reactions of Alkenes.</p> <p>40. Synthesis and Absolute Stereochemical Assignment of (-)-Galbulimima Alkaloid 13.</p> <p>41. Preparation of Benzene Derivatives.</p> <p>42. Preparation of Heteroaromatic Derivatives.</p> <p>43. Functional Group Transformation.</p> <p>44. Functional Group Protection.</p> <p>45. The Leighton Synthesis of Dolabelide D.</p> <p>46. Stereocontrolled Construction of N-Heterocycles.</p> <p>47. Stereocontrolled Construction of O-Heterocycles.</p> <p>48. Stereocontrolled Synthesis of O-Heterocyclic Natural Products.</p> <p>49. The Ready Synthesis of (-)-Nigellamine A<sub>2</sub>.</p> <p>50. Advances in the Diels-Alder Reaction: Synthesis of (+)-Lycoridine and of Dolabellatrienone.</p> <p>51. Enantioselective Carbocyclic Construction.</p> <p>52. Transition Metal Mediated Carbocyclic Construction.</p> <p>53. Synthesis of (-)-Colombiasin A and (-)-Elisapterosin B.</p> <p>54. Enantioselective Synthesis of C-N Ring Containing Natural Products.</p> <p>55. New Catalysts and Strategies for Alkene and Alkyne Metathesis.</p> <p>56. Heterocyclic Natural Products by Alkene Metathesis.</p> <p>57. Carbobyclic Natural Products by Alkene Metathesis.</p> <p>58. The Crimmins Synthesis of (+)-SCH 351448.</p> <p>59. Enantioselective Construction of Alcohols and Amines.</p> <p>60. Enantioselective Construction of Alkylated Stereogenic Centers.</p> <p>61. Enantioselective Construction of Arrays of Stereogenic Centers.</p> <p>62. The Sorensen Synthesis of (-)-Guanacastepene E.</p> <p>63. Selective Reactions of Alkenes.</p> <p>64. Best Synthetic Methods: C-C Bond Formation.</p> <p>65. Functional Group Protection and Deprotection.</p> <p>66. The Nicolaou Synthesis of Platensimycin.</p> <p>67. Stereocontrolled C-O Ring Construction.</p> <p>68. Stereocontrolled Natural Product Synthesis: Cyclic Ethers and Macrolides.</p> <p>69. Stereocontrolled C-N Ring Construction.</p> <p>70. Stereocontrolled Alkaloid Total Synthesis.</p> <p>71. The Fukuyama Synthesis of Morphine.</p> <p>73. Oxidation and Reduction in Organic Synthesis.</p> <p>73. Interconversion of Organic Functional Groups.</p> <p>74. Best Synthetic Methods: Carbon-Carbon Bond Formation.</p> <p>75. The Overman Synthesis of (-)-Sarah A.</p> <p>76. Recent Developments in Alkene Metathesis.</p> <p>77. Pushing the Limits of Alkene Metathesis in Natural Product Synthesis.</p> <p>78. Preparation of Benzene Derivatives.</p> <p>79. The Padwa Synthesis of Aspidophytidine.</p> <p>80. Synthesis of Heteroaromatics.</p> <p>8 1. Enantioselective Construction of Alcohols and Amines.</p> <p>82. Enantioselective Construction of Alkylated Stereogenic Centers.</p> <p>83. Enantioselective Construction of Arrays of Stereogenic Centers.</p> <p>84. The Gin Synthesis of Nominine.</p> <p>85. The Intramolecular Diels-Alder Reaction in Natural Product Synthesis.</p> <p>86. Catalytic Enantioselective Carbon-Carbon Ring Construction.</p> <p>87. New Directions in C-C Ring Construction: The Overman Synthesis of Guanacastepene N.</p> <p>88. The Pettus Synthesis of (+)-Rishirilide B.</p> <p>89. Selective Reactions of Alkenes.</p> <p>90. Selective C-H Functionalization.</p> <p>91. New Methods for Carbon-Carbon Bond Formation.</p> <p>92. The Nakada Synthesis of (+)-Digitoxigenin.</p> <p>93. Preparation of Benzene Derivatives.</p> <p>94. Preparation of Heteroaromatics: The Movassaghi Synthesis of (+)-Chimonanthine.</p> <p>95. Organic Functional Group Transformation.</p> <p>96. Organic Functional Group Protection.</p> <p>97. The Trost Synthesis of (-)-Terpestacin.</p> <p>98. Stereoselective C-N Ring Construction.</p> <p>99. Stereoselective C-0 Ring Construction.</p> <p>100. Synthesis of (-)-Blepharocalyxin D, (-)-Lasonolide A, and Attenol A.</p> <p>101. The Dark Synthesis of Vigulariol.</p> <p>102. Enantioselective Organocatalytic Synthesis of Carbocycles: The Iwabuchi Synthesis of (+)-Juvabione.</p> <p>103. Transition-metal Mediated Synthesis of Carbocycles: The Snapper Synthesis of Pleocarpenone.</p> <p>104. Enantioselective Construction of Carbocycles: The Williams Synthesis of (+)-Fusicoauritone.</p> <p>105. C-H Functionalization: The White Reagent.</p> <p>Author Index.</p> <p>Reaction Index.</p>
"Provides a rich source of information for the practicing chemist and highlights the diversity of reactions and methods in use." (<i>Journal of Medicinal Chemistry</i>)
<b>DOUGLASS F. TABER</b>, PhD, is Professor of Chemistry at the University of Delaware, Newark, Delaware. Professor Taber has published more than 170 articles in the organic chemistry field, and has authored eight chapters and several books. His research interests include the stereoselective synthesis of natural products, new methods in synthetic organic chemistry, and computational organometallic chemistry in organic synthesis.
<b>A convenient, compact summary of the state of the art of organic synthesis</b> <p>Organic synthesis is a vibrant and rapidly evolving field; we can now prepare ketones by directly combining aldehydes with terminal alkenes. Like the first book in this series, Organic Synthesis: State of the Art 2003–2005, this reference leads readers quickly to the most important recent developments. Two years' of Taber's popular weekly online column, "Organic Chemistry Highlights," as featured on the organic-chemistry.org Web site, are consolidated here, with cumulative indices of both volumes in this series. Important topics that are covered range from powerful new methods for C-C bond construction to asymmetric organocatalysis and direct C-H functionalization. This go-to reference:</p> <ul> <li>Focuses on the most important recent developments in organic synthesis, and includes a succinct analysis of the significance and applications of each synthesis</li> <li> <p>Details and analyzes more than twenty total syntheses, including the Davies Synthesis of (-)-Colombiasin A and (-)-Elisapterosin B, the Overman Synthesis of (-)-Sarain A, and the Sorensen Synthesis of (-)-Guanacastepene E</p> </li> <li> <p>Features cumulative reaction/transformation and author indices covering both books in the series so readers can quickly get up to date on a current topic</p> </li> </ul> <p>This series offers chemists an effective, efficient, timesaving way to stay abreast of what's new and exciting in organic synthesis.</p>

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